BGU develops new AI platform for monitoring and predicting ALS progression

first_imgReviewed by Alina Shrourou, B.Sc. (Editor)Feb 20 2019Technology will also improve drug development and clinical trials for neurodegenerative diseasesBen-Gurion University of the Negev (BGU) has developed a new artificial intelligence (AI) platform for monitoring and predicting progression of neurodegenerative diseases to help identify markers for personalized patient care and improve drug development.The platform, developed by Prof. Boaz Lerner of the BGU Department of Industrial Engineering and Management will initially be used for amyotrophic lateral sclerosis (ALS) and ultimately for Alzheimer’s, Parkinson’s and other neurodegenerative diseases.”One of the big challenges of designing and managing clinical trials for ALS is that it is a rare disease, and clinical variability makes it hard to identify markers for severity,” says Prof. Lerner. “As a result, after decades of research, there is still no real cure for ALS and several other challenging neurodegenerative diseases, including Alzheimer’s.”Our new technology will more accurately predict disease progression, a crucial ingredient for clinical trials, and better identify the interrelationships between demographics and other measurable factors identified through physical examinations and patient functionality.”ALS, also known as Lou Gehrig’s disease, is a fatal neurodegenerative disease that causes death of motor neurons which control voluntary muscles. This muscle atrophy leads to progressive weakness and paralysis, difficulty speaking, swallowing and breathing. The average survival time for people who are typically diagnosed between ages 40 to 60 is two to five years from onset of symptoms.Related StoriesUsing artificial intelligence to personalize the dose of radiation therapy for cancer patientsNovel imaging molecule reveals brain changes linked to progressive MSEndogenous retrovirus type W found to be a major contributor to nerve damage in MSALS population heterogeneity complicates research and drug development because of symptom variability at onset, disease progression rates and patterns, and survival statistics. This variability makes it difficult to predict disease progression rate and pattern for individuals.Having a reliable personalized prediction platform could improve patient care and quality of life for many patients and their caregivers. The new AI platform could also improve clinical trial design by identifying markers for various patient sub-populations’ treatment.The BGU platform integrates demographic and clinical data with machine learning and data mining algorithms to produce models that can predict the rate and pattern of ALS progression, identify specific lab tests or vital signs, and stratify similar sub-groups from the diverse ALS population. The algorithms, and their ability to predict disease progression, will improve as clinical data is added for each patient.”Now that the algorithms required to produce effective models have been established and evaluated, the funding we received from the Israel Innovation Authority will enable researchers to create a system that patients, physicians, caregivers, pharmaceutical companies, HMOs, and insurers can use on desktop and mobile applications to monitor and predict ALS progression,” says Itzik Mashiach at BGN Technologies, BGU’s technology-transfer company.”We are now seeking an industry partner to further develop and commercialize this innovative patent-pending technology.”​ Source:https://aabgu.org/nlast_img read more

Amazon primed to hire 2000 new employees in France

Explore further US online shopping giant Amazon said Thursday it plans to create 2,000 permanent full-time jobs in France this year as consumers are making more and more of their purchases via the internet. © 2018 AFP “The jobs are at all levels of skills” even if “the overwhelming majority of the positions are for fulfilling orders,” Amazon’s director in France Frederic Duval told AFP.The new jobs will be across Amazon’s distribution centres in France, as well as its offices in the Paris region, and take overall staff to 7,500.Amazon said it has invested more than two billion euros ($2.5 billion) in France since 2010 and created more than 1,500 jobs in France last year.However Amazon, along with other US tech companies, has also been at loggerheads with French authorities over taxes as they structure sales to pass through other European countries where tax rates are lower.Amazon announced earlier this month it had reached an agreement with French tax authorities under which it will now register French sales in France. The 2,000 new jobs will take Amazon’s overall workforce in France to 7,500 Amazon hammers out tax deal with France Citation: Amazon primed to hire 2,000 new employees in France (2018, February 15) retrieved 18 July 2019 from https://phys.org/news/2018-02-amazon-primed-hire-employees-france.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. read more

Five reasons why robots wont take over the world

Robots that can learn like humans Credit: Shutterstock Citation: Five reasons why robots won’t take over the world (2018, April 18) retrieved 18 July 2019 from https://phys.org/news/2018-04-robots-wont-world.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Provided by The Conversation Scientists are known for making dramatic predictions about the future – and sinister robots are once again in the spotlight now that artificial intelligence has become a marketing tool for all sorts of different brands. 1. Human-like handsScientists are far from replicating the complexity of human hands. The hands of robots that are used today in real applications are clumsy. The more sophisticated hands developed in labs are not robust enough and lack the dexterity of human hands. Comparison of a human hand with a robotic one. Credit: Wikimedia, CC BY At the end of World War Two, it was stated that flying cars were just around the corner and that all energy problems would be solved by fusion energy by the end of the 20th century. But decades on, we don’t seem much closer to either of those predictions coming true. So what’s with all this talk – fuelled by the likes of space baron, Elon Musk – about robots taking over the world? Pessimists predict that robots will jeopardise jobs across the globe, and not only in industrial production. They claim robot journalists, robot doctors and robot lawyers will replace human experts. And, as a consequence of a melting down middle class, there will be mass poverty and political instability. Optimists predict a new paradise where all the tedious problems of human relationships can be overcome by having a perfect life with easily replaceable robot partners, which will fulfil our basic needs as well as our deepest longings. And “work” will become an ancient concept. The pessimists, however, can relax and the optimists need to cool their boots. As experts in the field of robotics, we believe that robots will be much more visible in the future, but – at least over the next two decades – they will be clearly recognisable as machines. This is because there is still a long way to go before robots will be able to match a number of fundamental human skills. Here are five reasons why robots aren’t about to take over the world. This article was originally published on The Conversation. Read the original article. 5. Human reasonNot all of what is technically possible needs to be built. Human reason could decide not to fully develop such robots, because of their potential harm to society. If, in many decades from now, the technical problems mentioned above are overcome so that complex human-like robots could be built, regulations could still prevent misuse.Smooth out the edgesIn our research project, SMOOTH, we design robots that we hope will operate in elderly care institutions by 2022. These robots will be used to solve repetitive tasks involving human and robot interaction, such as transporting laundry and waste, offering water to people or guiding them to the breakfast table. It was necessary to simplify the robots as well as to carefully select the tasks they perform to ensure that they can be commercially viable products within four years.Our approach wasn’t to solve the first three problems of human-like hands, tactile perception and control of manipulation, but to avoid those robotic roadblocks. To address the fourth problem of human and robot interaction, we chose repetitive tasks to reduce complexity, since the expected interactions are – to a certain degree – predictable. Robots are a reality today in industry and they will appear in public spaces in more complex shapes than robot vacuum cleaners. But in the next two decades, robots will not be human-like, even if they might look like humans. Instead they will remain sophisticated machines. So you can stand down from any fear of a robot uprising in the near future. 2. Tactile perceptionThere is no technical match for the magnificent human and animal skin that encompasses a variety of tactile sensors. This perception is required for complex manipulation. Also, the software that processes the input from the sensors in robots is nowhere near as sophisticated as the human brain when it comes to interpretation and reaction to the messages received from the tactile sensors.3. Control of manipulationEven if we had artificial hands comparable to human hands and sophisticated artificial skin, we would still need to be able to design a way to control them to manipulate objects in a human-like way. Human children take years to do this and the learning mechanisms are not understood.4. Human and robot interactionThe interaction between humans is built on well-functioning speech and object recognition systems, as well as other sensors such as smell and taste and tactile sensing. While there has been significant progress in speech and object recognition, today’s systems can still only be used in rather controlled environments when a high degree of performance is required. Explore further read more

Karnataka launches SCST entrepreneurship schemeKarnataka launches SCST entrepreneurship scheme

first_imgSHARE October 30, 2018 Following the success of Unnati and Airavata schemes, Karnataka Social Welfare Department today launched the Samruddhi scheme to boost employment opportunities for SC/ST youth through entrepreneurship. For this, the government is partnering with private enterprises to train the youth from backward communities.“The government is planning to create ‘industry owned private enterprise’ to make them financially independent,” said State Minister for Social Welfare Priyank Kharge said.“The Samruddhi scheme is targeted at socially marginalised communities to provide them with skill development and alternate means of employment,” he added.To create industry owned private enterprise, the State government signed a memorandum of understanding (MoU) with 30 retail companies of the 62 which have shown interest.The 30 companies which have signed MoU are to provide self-employment opportunities for around 25,000 beneficiaries from the SC/ST communities.The department is hoping to create around 10,000 entrepreneurs annually in the next three years from among the economically and socially marginalised communities in the State.“These entrepreneurs will in their turn create jobs in rural and semi urban areas, and help push employment and skill development in the State further. The government hopes that this scheme will ultimately benefit aspiring, young citizens from rural and tier II cities and ensure sustainable and all-round development,” said Kharge.As part of the Samruddhi scheme, the government will also provide a seed grant to deserving youth to start their own franchises or retail outlets after they receive the required training and certification. COMMENTS SHARE SHARE EMAIL Karnataka social welfare COMMENT Published onlast_img read more

AP High Court CJ judges sworn in HC starts functioning in VijayawadaAP

first_imgjudiciary (system of justice) SHARE AP gets separate HC from January 1 RELATED COMMENTS courts and legal January 01, 2019 Vijayawada Andhra Pradesh got a separate High Court on New Year’s Day and the court is being temporarily housed in the Chief Minister’s camp office here.Chief Justice Praveen Kumar and other judges of the AP High Court were administered the Oath of Office at the Indira Gandhi municipal stadium on Tuesday by AP and Telangana Governor ESL Narasimhan. Andhra Pradesh Chief Minister N Chandrababu Naidu attended the swearing-in ceremony. The AP High Court staff arrived at Amaravati from Hyderabad in three private buses.CompletionAccording to Municipal Administration Minister P Narayana, the construction of the city civil courts building is underway at Nelapadu and will be completed by the end of the month after which the High Court would shift there. He said 16 court halls, 12 on the first floor, would be ready by the end of the month. He said the temporary court complex would have 2.70 lakh sq ft built-up area and was being built at a cost of ₹150 crore. COMMENT Published on SHARE SHARE EMAIL Governor ESL Narasimhan greets Chief Justice Praveen Kumar after swearing-in ceremony in Vijayawada on Tuesday. AP Chief Minister N Chandrababu Naidu is also seen   –  V Rajulast_img read more

As campaign concludes in AP Jagan Reddys remarks on Amaravati leave voters

first_imgpoll campaign SHARE SHARE EMAIL Andhra Pradesh April 09, 2019 As the campaigning concluded in Andhra Pradesh on Tuesday, for the poll to be held on Thursday, a doubt is lingering in the minds of voters, especially in Krishna and Guntur districts. It relates to Amaravati, the new capital.In interviews given to English and Telugu channels, the YSR Congress leader, YS Jagan Mohan Reddy, described Amaravati as a huge scam perpetrated by Chief Minister.‘Huge scam’On Tuesday, the last day when Jagan campaigned in Mangalagiri constituency in Guntur district in the new capital region, he explained to the voters the huge scam allegedly perpetrated by N Lokesh, Chief Minister Chandrababu Naidu’s son and State IT Minister, is contesting from Mangalagiri as the TDP candidate.Jagan said, “We also welcomed the decision initially, though we did not approve the method of arriving at the decision, and we had our reservations. But then the Chief Minister cleverly encouraged speculation on where exactly the capital will come up, knowing well the exact location and keeping it to himself and his friends and cronies, and giving an impression to the people that it might come up elsewhere.“His friends, cronies and benamis bought huge parcels of lands near the present location, Amaravati, at throwaway prices. Then, he announced the location. Others who bought land at other locations lost heavily… And the scam did not stop there.”He alleged that the Chief Minister acquired 33,000 acres from farmers through the land-pooling method, ensuring that the land-parcels of his cronies, friends and benamis were excluded from the core capital area.“The prices of these lands abutting the capital area shot up. The farmers who have lost the lands are very unhappy. Then, the CM started allotting the lands in the core capital area to companies in the name of capital development. It is a huge scam, the biggest in the history of the State,” Jagan Reddy alleged.On Tuesday, while campaigning in Guntur district, Chandrababu Naidu said, “If Jagan comes to power, all development in the State will come to a halt. In particular, Amaravati and the Polavaram project will suffer. He is not interested in Amaravati.”This issue will have a bearing on the minds of the voters in two very important coastal districts — Krishna and Guntur — though the rest of the State will also be affected to some extent.If he comes to power, what Jagan intends to do with Amaravati, which he describes as a huge scam, is anybody’s guess. Published on SHARE YS Jagan Mohan Reddy   –  CH VIJAYA BHASKAR political campaigns state politics Chandrababu Naidu COMMENT COMMENTSlast_img read more